Wednesday 14 May 2014

Antibiotic Resistance:



p The ability of pathogens that works against the antibiotics is termed Antibiotic Resistance.
p Antibiotic resistance may be caused by many factors including…
Ø Overuse
Ø Misuse
Ø Availability of OTC antibiotics
Ø Healthcare Workers
Ø Hospitalized Patients
Ø Animal Feed
Ø Antibiotics in food and water
Ø Antibiotic resistance in genetically modified crops
p There are three types of Antibiotic resistance such as…
Ø Natural or inherent resistance
Ø Mutational resistance
Ø Acquired (Extrachromosomal) resistance
p Bacterial resistance may be developed by the mechanisms like…
Ø Enzymatic degradation of the drug
Ø Modification of the drug's target
Ø Reduced permeability of the drug
Ø Efflux pumping of Antibiotics
Ø Modification of Target ribosomes
Ø Alteration of Pathway
p Antibiotic resistance may be reduced by
Ø Stop unnecessary antibiotic prescriptions
Ø Complete the course of antibiotic prescriptions
Ø Promote Vaccine recommendations
Ø Implement infection control measures, such as hand washing, isolation precautions, and immunization
Ø Improve communication, education and training.

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